Quick Answer: Does Sickle Cell Trait Cause Symptoms?

Can sickle cell trait cause health problems?

Sickle cell trait is NOT a disease and will never turn into a disease.

People with sickle cell trait usually do not have any health problems.

However, under extreme conditions a person with sickle cell trait can experience some of the same problems as a person who has sickle cell disease..

Does sickle cell trait cause fatigue?

Fatigue is a common symptom associated with sickle cell disease. Due to the smaller size of our red blood cells, we cannot carry as much oxygen as those with healthier red blood cells. This leads to a lack of oxygen in our bodies and, ultimately, fatigue.

Is Sickle cell trait an autoimmune disease?

Background. Patients with sickle cell disease (SCD) present a defective activation of the alternate complement pathway that increases the risk of infection and is thought to predispose to autoimmune disease (AID).

How long can you live with sickle cell trait?

With a national median life expectancy of 42–47 years, people with sickle cell disease (SCD) face many challenges, including severe pain episodes, stroke, and organ damage.

How is sickle cell trait diagnosed?

A blood test can check for the defective form of hemoglobin that underlies sickle cell anemia. In the United States, this blood test is part of routine newborn screening. But older children and adults can be tested, too. In adults, a blood sample is drawn from a vein in the arm.

Do both parents need to have the sickle cell trait?

Two genes for the sickle hemoglobin must be inherited from one’s parents in order to have the disease. A person who receives a gene for sickle cell disease from one parent and a normal gene from the other has a condition called “sickle cell trait.” Sickle cell trait produces no symptoms or problems for most people.

Who carries the sickle cell trait?

Sickle cell trait (also known as being a carrier) occurs when a person has one gene for sickle hemoglobin and one gene for normal hemoglobin. Approximately one in ten African-Americans carries sickle cell trait. People who are carriers generally do not have any medical problems and lead normal lives.

What happens if only one parent has sickle cell trait?

If one parent has sickle cell trait (HbAS) and the other has sickle cell anaemia (HbSS) there is a one in two(50%) chance that any given child will get sickle cell trait and a one in two chance that any given child will get sickle cell anaemia. No children will be completely unaffected.

Can sickle cell trait be cured?

The only known cure for sickle cell disease is bone marrow or stem cell transplant. Bone marrow is the soft tissue inside the bones that makes blood cells.

How common is sickle cell trait?

Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Sickle cell trait can also affect Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.

How old is the oldest person with sickle cell?

There are people with sickle cell living well past the average life expectancy. The oldest person currently living with sickle cell, Asiata Onikoyi-Laguda, is 94.

What blood type is sickle cell trait?

People who have these forms of SCD inherit one sickle cell gene (“S”) and one gene from an abnormal type of hemoglobin (“D”, “E”, or “O”). Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body.

Does sickle cell trait cause iron deficiency?

The prevalence of iron deficiency anaemia defined as the coexistence of Hb below 13 g/dl in adult males and below 12 in adult females and children with two laboratory indicators of iron deficiency, was 10.3% in the normal population as against 1.3% in the sickle cell trait group (P less than 0.008).

Can I donate blood if I have sickle cell trait?

Is it safe for people with sickle cell trait to donate blood? Yes. If you have sickle cell trait, you are still are able to donate blood. There is no evidence to suggest that donating blood causes any additional risk of harm or injury to people with sickle cell trait.

Can sickle cell trait skip a generation?

Sickle cell can only be passed on from parents to children. It is not contagious and it cannot skip a generation. The likelihood of having it depends on how many SC genes one or both parents have.

Can you fly with sickle cell trait?

People with sickle-cell trait are at risk if they fly in unpressurized aircraft, which are used for many local air services. Those with sickle-cell haemoglobin C disease should avoid air travel even in pressurized aircraft.

Can a white person have sickle cell?

Answer. Yes, they can. Sickle cell disease can affect people of ANY race or ethnicity. Sickle cell disease, an inherited disorder of the red blood cells, is more common in African Americans in the U.S. compared to other ethnicities—occurring in approximately 1 in 365 African Americans.

Does sickle cell trait affect breathing?

A lung infection or sickle cells blocking blood vessels in your lungs can cause this life-threatening complication, resulting in chest pain, fever and difficulty breathing.

What is the difference between sickle cell anemia and sickle cell trait?

What is the difference between sickle cell trait and sickle cell disease? People with sickle cell trait carry only one copy of the altered hemoglobin gene and rarely have any clinical symptoms related to the disease. In contrast, people with sickle cell disease carry two copies of the altered hemoglobin gene.

Why do only African American get sickle cell?

This condition is called “sickle cell trait.” People with sickle cell trait have enough normal hemoglobin in their red blood cells to prevent the cells from sickling. One in 12 African Americans in the United States has sickle cell trait.